SPR-DMD4000 Multi-Channel Dissolution Medium Degasser

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SPR-DMD4000 Multi-Channel Automatic Dissolution Medium Degasser

Product ID：HZYJtq009

Price: Please inquire PDF Format

Supply Ability:50SETS/MON

Port:SHENZHEN

Product Introduction
Other information

Model NumberSPR-DMD4000

Brand NameTJSAIPURUI

Payment TermsTT，PAYPAL，Alibaba.com Pay

SPR-DMD4000 Multi-Channel Automatic Dissolution Medium Degasser
Product Introduction
The SPR-DMD4000 Multi-Channel Automatic Dissolution Medium Degasser is an automated dissolution media degassing and dispensing system designed for pharmaceutical dissolution testing and full dissolution studies. It integrates automatic liquid aspiration, online preheating, vacuum degassing, quantitative dispensing, and multi-vessel filling into one automated workflow.
Using a vacuum negative-pressure degassing method with a vacuum level down to -0.095 MPa, the SPR-DMD4000 can achieve effective dissolution medium degassing while heating the medium to approximately 40°C, reducing the need for high-temperature treatment commonly associated with conventional tabletop vacuum degassers.
The system can process two different dissolution media simultaneously and dispense two degassed media to four dissolution vessels at the same time. For dispensing volumes of 500–1000 mL, the volume deviation is within ±1%, helping improve dissolution testing efficiency, consistency, and laboratory automation.

Performance Features
• Two-media simultaneous processing: Two different dissolution media can be processed at the same time.
• Automatic integrated operation: Combines liquid aspiration, preheating, vacuum degassing, quantitative dispensing, and multi-vessel filling.
• Four-vessel simultaneous dispensing: Two handles can simultaneously and precisely dispense two different degassed media into four dissolution vessels.
• High dispensing accuracy: Dispensing accuracy is within ±1% for volumes of 500–1000 mL.
• Efficient vacuum degassing: Vacuum level reaches -0.95 bar, providing effective degassing at relatively low medium temperatures.
• SDS-containing media compatibility: Supports dissolution media containing surfactant SDS at concentrations up to 2.0%.
• Automatic alarm system: LED indicators and audible alarms identify problems such as no liquid intake, insufficient liquid intake, excessive pressure, and communication faults.

Working Principle
The SPR-DMD4000 uses vacuum negative-pressure degassing technology to remove dissolved gases from dissolution media.
During operation, the system automatically draws the dissolution medium into the instrument and performs online preheating. The medium then enters the vacuum degassing process, where reduced pressure promotes the release and removal of dissolved gases. The degassed medium is subsequently delivered through the quantitative dispensing system to the designated dissolution vessels.
The system can process two different dissolution media independently and simultaneously. The dual-handle dispensing design enables two types of degassed media to be supplied to four dissolution vessels at the same time, reducing manual handling and improving the repeatability of dissolution medium preparation and dispensing.

Technical Parameters

Parameter	Specification
Model	SPR-DMD4000
Instrument Type	Multi-Channel Automatic Dissolution Medium Degasser
Number of Media Types	2
Number of Dispensing Channels	4
Quantitative Dispensing Volume per Channel	250–1000 mL
Dispensing Accuracy	±1% of set volume at 500–1000 mL
Preparation Time	Four channels simultaneously: average ≤70 s per 1000 mL vessel
Preparation Time	One group/two dispensing channels: average ≤135 s per 1000 mL vessel
SDS-Containing Medium Capacity	≤2.0%
Heating Function	Initial temperature increase of 20°C
Maximum Supply Temperature	Up to 45°C, depending on initial temperature
Temperature Accuracy	±2°C
Vacuum Level	-0.95 bar
Working Noise	<60 dB
Operating Environment	5–35°C; relative humidity ≤80%
Power Supply	AC 220 V, 50 Hz, 10 A
Rated Power	≤2200 W
Dimensions	738 × 650 × 1348 mm (L × W × H)
Weight	Approx. 150 kg

Application Scenarios
The SPR-DMD4000 Multi-Channel Automatic Dissolution Medium Degasser is suitable for:
• Pharmaceutical R&D laboratories: Automated preparation and dispensing of dissolution media for drug development.
• Dissolution testing: Preparation of degassed dissolution media before dissolution testing.
• Full dissolution studies: Efficient preparation of dissolution media for high-volume experimental workflows.
• Quality control laboratories: Standardized dissolution medium preparation and quantitative dispensing.
• Multi-vessel dissolution testing: Simultaneous supply of degassed media to multiple dissolution vessels.
• High-throughput laboratories: Automation of repetitive dissolution medium preparation and dispensing operations.

Comparison: SPR-DMD4000 vs. Conventional Manual or Tabletop Degassing

Feature	SPR-DMD4000	Conventional Tabletop Vacuum Degasser / Manual Operation
Operation	Automated	Manual or semi-automated
Degassing Method	Vacuum negative-pressure degassing	Vacuum degassing or manual methods
Vacuum Level	-0.95 bar	Typically lower vacuum performance
Heating Requirement	Effective degassing at relatively low temperature	May require higher heating temperature
Media Types	2 media types simultaneously	Usually one medium at a time
Dispensing	Automatic quantitative dispensing	Manual dispensing or separate equipment
Multi-Vessel Filling	4 vessels simultaneously	Usually requires manual operation
Dispensing Accuracy	±1% at 500–1000 mL	Depends on operator/equipment
Automation	One-button automated workflow	Multiple manual steps
Alarm System	Automatic fault alarm	Usually limited
Laboratory Efficiency	High	Lower for repetitive high-volume testing

FAQ
1. What is the SPR-DMD4000 used for?
The SPR-DMD4000 is designed for automatic degassing and quantitative dispensing of dissolution media used in pharmaceutical dissolution and full dissolution testing.
2. How many different dissolution media can the instrument process simultaneously?
The SPR-DMD4000 can simultaneously process two different dissolution media.
3. How many dissolution vessels can be supplied at the same time?
The system can simultaneously dispense two different degassed dissolution media to four dissolution vessels.
4. What is the dispensing accuracy?
For dispensing volumes of 500–1000 mL, the dispensing volume deviation is within ±1% of the set volume.
5. What vacuum level does the SPR-DMD4000 provide?
The specified vacuum level is -0.95 bar, equivalent to approximately -0.095 MPa.
6. Can the instrument process dissolution media containing SDS?
Yes. The SPR-DMD4000 supports dissolution media containing SDS at concentrations up to 2.0%.
7. What is the dispensing temperature?
The system can provide a supply temperature of up to 45°C, depending on the initial temperature of the dissolution medium.
8. How does the SPR-DMD4000 improve laboratory efficiency?
It integrates liquid aspiration, preheating, vacuum degassing, quantitative dispensing, and multi-vessel filling into one automated process, reducing repetitive manual operations and improving dissolution testing efficiency and consistency.

FAQ
1. What is the SPR-DMD4000 used for?
The SPR-DMD4000 is designed for automatic degassing and quantitative dispensing of dissolution media used in pharmaceutical dissolution and full dissolution testing.
2. How many different dissolution media can the instrument process simultaneously?
The SPR-DMD4000 can simultaneously process two different dissolution media.
3. How many dissolution vessels can be supplied at the same time?
The system can simultaneously dispense two different degassed dissolution media to four dissolution vessels.
4. What is the dispensing accuracy?
For dispensing volumes of 500–1000 mL, the dispensing volume deviation is within ±1% of the set volume.
5. What vacuum level does the SPR-DMD4000 provide?
The specified vacuum level is -0.95 bar, equivalent to approximately -0.095 MPa.
6. Can the instrument process dissolution media containing SDS?
Yes. The SPR-DMD4000 supports dissolution media containing SDS at concentrations up to 2.0%.
7. What is the dispensing temperature?
The system can provide a supply temperature of up to 45°C, depending on the initial temperature of the dissolution medium.
8. How does the SPR-DMD4000 improve laboratory efficiency?
It integrates liquid aspiration, preheating, vacuum degassing, quantitative dispensing, and multi-vessel filling into one automated process, reducing repetitive manual operations and improving dissolution testing efficiency and consistency.