SPR-DMD1600 Dissolution Medium Degassing System

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SPR-DMD1600 Dissolution Medium Degassing System

Product ID：HZYJtq010

Price: Please inquire PDF Format

Supply Ability:50SETS/MON

Port:SHENZHEN

Product Introduction
Other information

Model NumberPR-DMD1600

Brand NameTJSAIPURUI

Payment TermsTT，PAYPAL，Alibaba.com Pay

SPR-DMD1600 Dissolution Medium Degassing System
Automatic Vacuum Degassing and Quantitative Filling Instrument

Product Introduction
The SPR-DMD1600 Dissolution Medium Degassing System is a professional dissolution medium degasser and automatic filling system designed for pharmaceutical dissolution testing laboratories. It integrates automatic liquid suction, online preheating, vacuum degassing, filtration, quantitative dispensing, and multi-vessel filling functions into one compact instrument.
During dissolution testing, dissolved gases in the medium may affect hydrodynamic conditions and lead to inaccurate results. The SPR-DMD1600 efficiently removes dissolved oxygen from dissolution media while maintaining precise temperature and filling volume control.
By replacing complicated manual preparation procedures, the automatic dissolution medium degassing system improves workflow efficiency, reduces operation errors, and ensures consistent dissolution testing conditions.

Performance Features
•   Integrated degassing and filling system
Combines filtration, heating, vacuum degassing, and quantitative liquid dispensing in one device.
•   High-efficiency vacuum degassing technology
Reduces dissolved oxygen content in dissolution media and improves dissolution test reliability.
•   Automatic liquid handling
Supports automatic suction, processing, and filling to minimize manual operation.
•   Precise quantitative dispensing
Provides accurate dissolution medium volume control for repeatable experiments.
•   Online preheating function
Maintains suitable medium temperature before filling into dissolution vessels.
•   Real-time parameter monitoring
Displays important operating parameters including heating temperature and vacuum level.
•   Wide compatibility with dissolution media
Supports regular dissolution media and media containing surfactants such as SDS.
•   Compact and user-friendly design
Small footprint and simple operation suitable for modern pharmaceutical laboratories.
•   Mobile platform option
Optional dedicated mobile workstation allows convenient movement and service for multiple dissolution testers.

Working Principle
The SPR-DMD1600 Dissolution Medium Degassing System operates through a combined process of filtration, heating, vacuum degassing, and accurate dispensing.
First, the dissolution medium passes through a 25 μm metal mesh pre-filter to remove impurities. The system then performs online heating to reach the preset temperature range.
Under controlled vacuum conditions, the dissolved gases inside the liquid are released and removed, significantly reducing dissolved oxygen levels. After degassing, the system automatically measures and dispenses the required volume into dissolution vessels.
This integrated process prevents air from being introduced during manual filling and ensures stable temperature, volume, and gas content conditions for dissolution testing.

Technical Parameters

Parameter	Specification
Product Name	SPR-DMD1600 Dissolution Medium Degassing System
Function	Dissolution medium degassing and automatic filling
Quantitative Dispensing Volume	250–1000 mL
Dispensing Accuracy	±1% of set volume (500–1000 mL range)
Preparation Time	≤3 min (1000 mL non-surfactant medium)
SDS Solution Processing Time	≤3 min (1000 mL water solution containing 2% SDS)
Maximum SDS Concentration	2.0% surfactant-containing medium
Maximum Heating Power	1000 W
Heating Function	More than 20℃ above initial temperature
Maximum Filling Temperature	Up to 45℃ (depending on initial temperature)
Temperature Accuracy	±2℃
Maximum Vacuum Degree	-0.95 bar
Degassing Performance	Effectively reduces dissolved oxygen content
Filtration System	Front-mounted 25 μm metal mesh filter

Application Scenarios
1. Pharmaceutical Dissolution Testing Laboratories
Used for preparing and supplying dissolution media for tablet and capsule dissolution tests.
2. Drug Quality Control
Ensures consistent dissolution conditions and improves reliability of pharmaceutical release testing.
3. Pharmaceutical Research and Development
Supports formulation studies and dissolution profile evaluation.
4. GMP Pharmaceutical Production
Helps laboratories standardize dissolution medium preparation and reduce manual operation errors.
5. Multi-Dissolution Tester Workstations
With the optional mobile platform, one SPR-DMD1600 system can provide dissolution media preparation services for multiple dissolution testers.

SPR-DMD1600 vs Traditional Manual Dissolution Medium Preparation

Feature	SPR-DMD1600 Automatic Degassing System	Traditional Manual Preparation
Degassing Method	Automatic vacuum degassing	Manual or external degassing
Filling Operation	Automatic quantitative filling	Manual measurement
Temperature Control	Online heating and monitoring	Manual temperature adjustment
Dissolved Oxygen Control	Stable and repeatable	Easily affected by operation
Preparation Efficiency	≤3 minutes for 1000 mL	Longer preparation time
Operation Accuracy	High precision volume control	More operator dependent
Workflow	Integrated filtration, heating, degassing, filling	Multiple separate steps

Frequently Asked Questions (FAQ)
1. What is the SPR-DMD1600 Dissolution Medium Degassing System used for?
The SPR-DMD1600 is used to automatically prepare dissolution media through filtration, heating, vacuum degassing, and quantitative filling for pharmaceutical dissolution tests.
2. Why is dissolution medium degassing important?
Dissolved gases in the medium can affect dissolution behavior and testing accuracy. Degassing improves test consistency and repeatability.
3. What volume range can the SPR-DMD1600 dispense?
The system supports quantitative dispensing volumes from 250 mL to 1000 mL.
4. Can the SPR-DMD1600 process SDS-containing dissolution media?
Yes. It can process dissolution media containing up to 2.0% SDS surfactant.
5. How long does the SPR-DMD1600 take to prepare dissolution media?
For 1000 mL dissolution medium, preparation can be completed within 3 minutes under specified conditions.
6. What is the maximum vacuum level of the system?
The maximum vacuum degree can reach -0.95 bar for effective degassing performance.
7. Does the system control dissolution medium temperature?
Yes. The SPR-DMD1600 provides online heating and temperature monitoring with accuracy of ±2℃.
8. What type of filtration does the instrument use?
The system uses a front-mounted 25 μm metal mesh filter for preliminary filtration.

Frequently Asked Questions (FAQ)
1. What is the SPR-DMD1600 Dissolution Medium Degassing System used for?
The SPR-DMD1600 is used to automatically prepare dissolution media through filtration, heating, vacuum degassing, and quantitative filling for pharmaceutical dissolution tests.
2. Why is dissolution medium degassing important?
Dissolved gases in the medium can affect dissolution behavior and testing accuracy. Degassing improves test consistency and repeatability.
3. What volume range can the SPR-DMD1600 dispense?
The system supports quantitative dispensing volumes from 250 mL to 1000 mL.
4. Can the SPR-DMD1600 process SDS-containing dissolution media?
Yes. It can process dissolution media containing up to 2.0% SDS surfactant.
5. How long does the SPR-DMD1600 take to prepare dissolution media?
For 1000 mL dissolution medium, preparation can be completed within 3 minutes under specified conditions.
6. What is the maximum vacuum level of the system?
The maximum vacuum degree can reach -0.95 bar for effective degassing performance.
7. Does the system control dissolution medium temperature?
Yes. The SPR-DMD1600 provides online heating and temperature monitoring with accuracy of ±2℃.
8. What type of filtration does the instrument use?
The system uses a front-mounted 25 μm metal mesh filter for preliminary filtration.