Plasma mass spectrometry ICP-MS
Plasma mass spectrometry ICP-MS
 
ICP-MS has the advantages of high sensitivity, low detection limit, good selectivity, wide coverage of measurable elements, wide linear range, multi-element detection and isotope ratio determination. It is a kind of trace (ultra-trace) inorganic multi-element analysis technology with broad prospects. It is widely used in the fields of environment, metallurgy, biology, medicine and nuclear material analysis to become the most powerful elemental analysis technology.
Instrument composition

The main components of ICP-MS include injection system, ion source, interface, ion lens, octopole collision cell, quadrupole mass filter, detector and vacuum system. The auxiliary equipment includes circulating cooling water system, Gas supply system, ventilation system and so on.
Working Principle and Analytical Characteristics of Plasma Mass Spectrometry ICP-MS

The sample is fed into the ICP source through the injection system and is evaporated, dissociated, atomized and ionized in a high temperature torch. Most of the metal ions become monovalent ions, which are rapidly passed through the biconical interface (sampling cone and truncation cone, 1 level vacuum) into the mass spectrometer vacuum system. After passing through the interface, the ions are focused into an ion beam by the electric field of the ion lens (2-stage vacuum) and into the quadrupole ion separation system (3-stage vacuum). Ion into the quadrupole mass analyzer, according to the mass / charge ratio of different in turn. Finally by the ion detector for detection, the resulting signal amplified by the signal detection system detected.

Compared to traditional inorganic analytical techniques, ICP-MS provides the lowest detection limits, the broadest dynamic linear range, minimal interference, high analytical precision, fast analysis, simultaneous multi-element determination, and Provide accurate isotope information and other analytical features.

ICP-MS has a simple spectral line and a flexible detection mode: (1) Qualitative analysis based on the mass-to-charge ratio of the line; (2) Determination of the approximate concentration range of all the elements by full line scan, (3) Quantitative analysis with standard solution calibration, which is the most widely used function in routine analysis; (4) Isotope ratio determination is a method of mass spectrometry An important function of ICP-MS is that it can be used for traceability studies and isotope tracers in geology, biology and TCM research.
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